Hotels in South San Francisco

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Where to stay in South San Francisco?

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top neighborhoods in South San Francisco

Top landmarks in South San Francisco

Learn more about South San Francisco

South San Francisco is well-known for its castle while top attractions include San Francisco Bay. Visitors to this family-friendly city speak highly of the restaurants whereas sights include South San Francisco Convention Center and Santa Cruz Mountains.

Frequently asked questions

Where can I get free parking at my hotel in South San Francisco?
Park your car for free at Americana Inn.
Can I book refundable accommodations in South San Francisco?
If you need the flexibility to change your travel plans to South San Francisco, most accommodations offer refundable* bookable rates. You can find these properties by searching our site and using the “fully refundable” filter to narrow down the results.
Where can I stay with my pet in South San Francisco?
Your animal companion is welcome at these pet-friendly hotels: DoubleTree by Hilton San Francisco South Airport Blvd, La Quinta Inn & Suites by Wyndham San Francisco Airport N, and Home2 Suites by Hilton San Francisco Airport North. There are 22 options on our site to choose from.
Which South San Francisco hotels do our guests like for their central location?
Travelers like DoubleTree by Hilton San Francisco South Airport Blvd for its great location.
Where should I stay in South San Francisco if I'm looking for a reasonably priced accommodation?
La Quinta Inn & Suites by Wyndham San Francisco Airport N is an accommodation you might want to consider that’ll save you money. You can browse all 18 choices on our site.
Where can I stay in South San Francisco if I want a vacation rental instead of a hotel?
If you’re looking for a good alternative to a hotel, review our selection of 59 vacation homes. In addition, you can choose from 12 apartments.
Where can I stay if I'm traveling to South San Francisco with my children?
Parents traveling with children may want to consider La Quinta Inn & Suites by Wyndham San Francisco Airport N, Embassy Suites San Francisco Airport - South San Francisco and Best Western Plus Grosvenor Airport Hotel. You can also see 8 options available on our site.
Where should I stay in South San Francisco for a getaway with my partner?
Inn At Oyster Point, La Quinta Inn & Suites by Wyndham San Francisco Airport N and Comfort Inn and Suites San Francisco Airport North are great options for a romantic getaway. You can also check out all 8 options on our site.
Where should I stay in South San Francisco if I want a luxurious hotel?
An option for a luxury stay is DoubleTree by Hilton San Francisco South Airport Blvd. Additionally, check out all 9 options on our site.
What will the weather in South San Francisco be like during my visit?
The warmest months in South San Francisco are usually September and August with an average temp of 62°F. February and January are the chilliest months when the average temp is 53°F. The rainiest months are December and January.
Why should I book my South San Francisco accommodation with Hotels.com?
There are lots of reasons to book your South San Francisco trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.