Hotels in Santee

your current months are December, 2024 and January, 2025.
December 2024
January 2025

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Where to stay in Santee?

Lewis and Clark Resort
32-inch LCD TV with digital channels, TV

Lewis and Clark Resort

2.5 star property
8.6 out of 10, Excellent, (186)
The price is P5,538
P5,854 total
includes taxes & fees
Dec 23 - Dec 24
Lewis and Clark Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top landmarks in Santee

Niobrara featuring a river or creek and boating as well as a small group of people

Niobrara State Park

Explore the great outdoors at Niobrara State Park, a lovely green space in Niobrara.

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Niobrara State Park

Learn more about Santee

The region around Santee is home to attractions such as Lewis and Clark Lake and Niobrara State Park.

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Frequently asked questions

Can I book refundable hotels in Santee?
If you want the flexibility to change your plans to Santee, most hotels provide refundable* rates you can book. You can find these properties by searching our site and using the “fully refundable” filter to narrow down the results.
What will the weather in Santee be like during my visit?
The warmest months in Santee are usually July and August with an average temp of 72°F. January and February are the chilliest months when the average temp is 26°F. The rainiest months are June and May.
Why should I book my Santee accommodation with Hotels.com?
There are lots of reasons to book your Santee trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.