Hotels in Mesopotamia

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February 2025
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Where to stay in Mesopotamia?

O2 Hotel Gualeguaychú
Front of property

O2 Hotel Gualeguaychú

2.5 star property
7.6 out of 10, Good, (52)
The price is P2,774
P2,774 total
includes taxes & fees
Jan 16 - Jan 17
O2 Hotel Gualeguaychú
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top landmarks in Mesopotamia

El Palmar National Park

El Palmar National Park

Explore the great outdoors at El Palmar National Park, a lovely green space in Ubajay.

See properties in El Palmar National Park
El Palmar National Park

Learn more about Mesopotamia

Notable for its natural beauty, Mesopotamia features attractions such as Termas de Chajarí and Termas de Federacion. This romantic city has something for everyone including sights like Concordia Speedway and Termas de La Paz.

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Mesopotamia featuring a river or creek and forest scenes

Frequently asked questions

What hotels do travelers like in Mesopotamia?
Casa Chic Carmelo, Club Valle Termal Resort and Costarenas Hotel & Spa are all accommodations that are popular with guests.
Can I book a refundable accommodation in Mesopotamia?
If you’re looking for the flexibility to change your plans to Mesopotamia, most properties offer refundable* bookable rates. You can find these accommodations by searching our site and using the “fully refundable” filter to narrow the results down.
Where should I consider staying in Mesopotamia if I want a budget-friendly accommodation?
An inexpensive option worth considering is O2 Gualeguaychú.
Where can I stay in Mesopotamia if I want a vacation rental instead of a traditional hotel?
Browse 13 vacation homes on our site. You also might want to consider one of 18 apartments or 10 cabins.
Why should I book my Mesopotamia hotel through Hotels.com?
There are lots of reasons to book your Mesopotamia trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.