Hotels in Syracuse

your current months are December, 2024 and January, 2025.
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Where to stay in Syracuse?

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top neighborhoods in Syracuse

Top landmarks in Syracuse

Learn more about Syracuse

Admired for its rich culture and seaside, Syracuse features attractions such as Temple of Apollo and Lungomare di Ortigia. This historical city has something for everyone including its archaeological sites, cafes, and sights like Piazza del Duomo and Cathedral of Syracuse.

Syracuse showing street scenes as well as an individual femail

Frequently asked questions

Can I book a refundable hotel in Syracuse?
If you’re looking for the flexibility to change your plans to Syracuse, most properties offer refundable* rates you can book. You can find these accommodations by searching our site and using the “fully refundable” filter to narrow down the results.
Where can I stay with my pet in Syracuse?
Your animal companion is welcome at these pet-friendly hotels: Palazzo Artemide - VRetreats, Ortea Palace Hotel, Sicily, Autograph Collection, and 300 mt. from the famous beach of Fontane bianche/Villa di Charme/7 Rooms7 Bathrooms. There are 105 alternatives on our site to choose from.
Which Syracuse hotels do our guests like for their central location?
Our guests love these properties for their good location: Algila’ Ortigia Charme Hotel and Palazzo Artemide - VRetreats.
Where can I stay in Syracuse if I want a vacation home instead of a hotel?
If you want to find a good alternative to a hotel, review our selection of 328 vacation homes. You can also book one of 1001 apartments or 422 villas.
Where can I stay if I'm visiting Syracuse with my family?
Parents traveling with children may want to consider Algila’ Ortigia Charme Hotel, VOI Arenella Resort and 300 mt. from the famous beach of Fontane bianche/Villa di Charme/7 Rooms7 Bathrooms. You can also check out 67 available options on our site.
Where should I stay in Syracuse for a vacation with my partner?
300 mt. from the famous beach of Fontane bianche/Villa di Charme/7 Rooms7 Bathrooms, “B&B” Casa D’Alleri “Quadruple room in a historic home in” Ortigia “ and “B&B Casa D’Alleri” Double Rooms in a historic home in “Ortigia” are a few good options for a romantic getaway with your special someone. You can also see all 7 options on our site.
Where should I stay in Syracuse if I want a luxurious hotel?
Experience luxury when you stay at Grand Hotel Ortigia Siracusa, Wellness & Spa Hotel Principe di Fitalia and Minareto. Additionally, check out all 6 options on our site.
What will the weather in Syracuse be like during my trip?
August and July are typically the warmest months in Syracuse when the average temp is 78°F. February and January are the coldest months when the average temperature is 56°F. November and October are the months with the most rain.
Why should I book my Syracuse hotel with Hotels.com?
There are lots of reasons to book your Syracuse trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.