In the heart of historic Hannibal, Main Street Bed & Breakfast welcomes you with continental breakfast and free WiFi. Enjoy valet parking, explore the nearby Mark Twain Boyhood Home and Museum or catch a show at Planters Barn Theater. Previous guests rave about this charming B&B’s location.
Corner of Main and Center, 201 North Main, Hannibal, MO, 63401
What's nearby
Big River Train Town - 3 min walk
Mark Twain Boyhood Home and Museum - 3 min walk
Mark Twain Memorial Lighthouse - 6 min walk
Rockcliffe Mansion - 11 min walk
Lovers Leap - 2 min drive
Getting around
Quincy, IL (UIN-Quincy Regional-Baldwin Field) - 30 min drive
St. Louis Lambert Intl. Airport (STL) - 107 min drive
Quincy Station - 28 min drive
Restaurants
McDonald's - 4 min drive
Casey's General Store - 4 min drive
Subway - 5 min drive
Sonic Drive-In - 4 min drive
Taco Bell - 4 min drive
About this property
Main Street Bed & Breakfast
Main Street Bed & Breakfast offers a great location, putting you within just a 10-minute walk of Mississippi River. Freebies like valet parking and self parking are added perks, and guests looking to stay active can check out the nearby kayaking and mountain biking. Fellow travelers love the location.
Languages
English
At a glance
Hotel size
3 rooms
Arriving/Leaving
Check-in start time: 2:00 PM; Check-in end time: 9:00 PM
Contactless check-in available
Early check-in subject to availability
Minimum check-in age: 21
Check-out time is 11:00 AM
Contactless check-out available
Required at check-in
Credit card, debit card, or cash deposit required for incidental charges
Government-issued photo ID may be required
Minimum check-in age is 21
Pets
Pets not allowed
Internet
Free WiFi in public areas
Parking
Free onsite self parking
Free onsite valet parking
Free onsite RV/bus/truck parking
Electric vehicle charging point on site
Other information
Smoke-free property
No stag/bachelor or hen/bachelorette parties
Property amenities
What to do
Mountain biking nearby
Kayaking nearby
Fishing nearby
Room amenities
Sleep well
Soundproofed rooms
Freshen up
Free toiletries
More
Daily housekeeping
Fees & policies
Optional extras
Wired internet access is available in public areas for an extra charge
Policies
This property's policy is to refuse certain bookings for the purpose of group events or parties, including pre-wedding stag/bachelor and hen/bachelorette parties.
This property does not have elevators.
Guests can rest easy knowing there's a fire extinguisher and a security system on site.
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).
This property accepts credit cards.
Also known as
Main Street Bed & Breakfast Hannibal
Main Street Bed & Breakfast
Main Street Bed & Breakfast Hannibal
Main Street Hannibal
Bed & breakfast Main Street Bed & Breakfast Hannibal
Hannibal Main Street Bed & Breakfast Bed & breakfast
Main Street Bed Breakfast
Bed & breakfast Main Street Bed & Breakfast
Main Street
Main Street Hannibal
Main Street & Hannibal
Main Street Bed Breakfast
Main Street Bed & Breakfast Hannibal
Main Street Bed & Breakfast Bed & breakfast
Main Street Bed & Breakfast Bed & breakfast Hannibal
Frequently asked questions
Are pets allowed at Main Street Bed & Breakfast?
Sorry, pets aren't allowed.
Is parking offered on site at Main Street Bed & Breakfast?
Yes, there's free self and valet parking. Free RV/bus/truck parking and electric vehicle charging are available.
What are the check-in and check-out times at Main Street Bed & Breakfast?
Check-in start time: 2:00 PM; Check-in end time: 9:00 PM. Check-out time is 11:00 AM. Contactless check-in and check-out are available.
What is there to do at Main Street Bed & Breakfast and nearby?
Have fun with nearby activities like cycling, fishing, and kayaking. Additional recreation nearby includes birdwatching.
What's the area around Main Street Bed & Breakfast like?
Main Street Bed & Breakfast is a short 5-minute walk from Mississippi River and 3 minutes' walk from Mark Twain Boyhood Home and Museum. Travelers give top marks for the bed & breakfast's prime location.
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Main Street Bed & Breakfast Reviews
Reviews
9.2
Wonderful
All reviews shown are from real guest experiences. Only travelers who have booked a stay with us can submit a review. We verify reviews according to our guidelines and publish all reviews, positive or negative.More informationOpens in a new window
9.8/10
Cleanliness
9.6/10
Staff & service
9.2/10
Amenities
9.2/10
Property conditions & facilities
9.2/10
Eco-friendliness
Reviews
8/10 Very good
October 5, 2024
Fun vintage building in great location. Staff friendly and full of information.
Judysharon
Judysharon, 1-night trip
10/10 Exceptional
July 24, 2024
Gracious host, location, location, location!
Chad
Chad, 1-night trip
10/10 Exceptional
June 24, 2023
Very beautiful place to stay. I would definitely stay there again my wife loved it!
Paul
Paul, 1-night trip
8/10 Very good
April 15, 2024
Host was very nice, location downtown we were able to walk everywhere even the lighthouse, tough walk, fresh baked bread added plus, we will be staying here again as granddaughter has three more years of college nearby.
Penny
Penny, 2-night trip
10/10 Exceptional
October 7, 2022
Beautiful room in a great location near most of the sights in Hannibal.
Gregory
Gregory, 1-night trip
10/10 Exceptional
April 3, 2024
Historic building in historic center of Hannibal!
DBenjamin
DBenjamin, 1-night trip
10/10 Exceptional
April 13, 2024
This was a terrific place to stay while in Hannibal. Right in the middle of all the Mark Twain sites. The room was full of fantastic old school charm. Really happy with the stay
Bret
Bret, 1-night trip
10/10 Exceptional
November 15, 2023
The room and decor were amazing!
Melissa
Melissa, 1-night trip
10/10 Exceptional
July 14, 2023
Very nice place
David
David, 1-night trip
8/10 Very good
March 9, 2024
This is right in the middle of this cute little downtown area. Walkable to all shops and dining.
Kaylene
Kaylene, 2-night trip
10/10 Exceptional
July 3, 2022
Great place with themed rooms.Historic site with lots of charm.
Mickey
Mickey, 1-night trip
10/10 Exceptional
October 31, 2023
Wonderful old building with architectural details. Very close to shopping and eateries.
Mary
Mary, 1-night trip
10/10 Exceptional
November 27, 2023
Such an amazing room--very romantic, perfect for our anniversary
Clark
Clark, 1-night trip
10/10 Exceptional
May 22, 2024
We stayed at the Main Street Bed and Breakfast to be close to the historic part of the town. It was in a perfect location. We walked to several attractions, restaurants and bars. The room was very large and had a nice refrigerator and a great shower. The owner was really nice and welcomed us upon arrival.
Michele
Michele, 1-night trip
10/10 Exceptional
July 17, 2022
A great little place to stay right in the heart of downtown Hannibal. The property is fantastic and Michael is an excellent host.
Vincent
Vincent, 1-night trip
10/10 Exceptional
June 8, 2023
Great stay! The highlights are a smooth check-in process with a great host, plenty of parking, a very comfortable bed, a spacious en suite bathroom, and a cute walkable downtown area with plenty of dining options. I stayed one night while passing through town, and I highly recommend staying longer and exploring the area if you can.
Shalimar
Shalimar, 1-night trip
10/10 Exceptional
April 10, 2023
Beautiful Historic Bed & Breakfast. I definitely recommend.
Barbara
Barbara, 1-night trip
10/10 Exceptional
August 9, 2023
Great place to stay and very reasonably priced! Right in town and just one block from the Mississippi river and attractions. Our room had a huge jacuzzi tub, comfy bed. Nice host.
Cathy
Cathy, 1-night trip
10/10 Exceptional
November 4, 2022
Lovely property, beautiful accommodations. Our host extremely helpful in recommending dinner options sightseeing ideas. Very friendly and personable…we intend to return.
Esther
Esther, 1-night trip
6/10 Good
March 17, 2024
Good value
Danny
Danny, 1-night trip
8/10 Very good
December 31, 2022
Loved the old building and the look and feel of history!!
Theresa
10/10 Exceptional
August 15, 2023
Right in town and just one block from the Mississippi river .
Edvard
Edvard, 1-night trip
10/10 Exceptional
December 29, 2022
Great location! Super cool old building.
I would (and hope to) stay there again.
Shawn
Shawn, 1-night trip
10/10 Exceptional
August 25, 2024
Mike is a great, easy-going guy. He gave us early access to the building & room. Convenient digital touchpad entry. He retained all the original woodwork, doors & windows that give the building a wonderful historic vibe. There is no better place to be centrally located for all of the downtown restaurants, shops, & historical sites.
Russell
Russell, 2-night trip
10/10 Exceptional
October 24, 2023
Cozy stay. Hop in the hot tub and sip some grape juice