Photo by Fabrice Récalt

Hotels in Santana

your current months are January, 2025 and February, 2025.
January 2025
February 2025

Find and book your perfect stay

Earn rewards on every night you stay
Save more with Member Prices
Free cancellation options if plans change

Where to stay in Santana?

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Santana

The region around Santana is home to attractions such as Estadio Nacional 12 de Julho and Cathedral of São Tomé.

Photo by Fabrice Récalt
Open Photo by Fabrice Récalt

Frequently asked questions

Can I book refundable accommodations in Santana?
If you want the flexibility to change your travel plans to Santana, most hotels offer refundable* rates you can book. You can see these properties by searching our site and using the “fully refundable” filter to narrow down the results.
Where can I stay if I'm visiting Santana for a family-friendly trip?
Parents traveling with children may want to consider Roça Santo António Ecolodge Hotel.
What will the weather in Santana be like during my trip?
Santana is a great place to visit any time of year with an average temperature of 77°F during the coldest months.
Why should I book my Santana hotel with Hotels.com?
There are lots of reasons to book your Santana trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.