Hotels in Panacea

October 2026
November 2026

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This weekend
Oct 2 - Oct 4
Next weekend
Oct 9 - Oct 11

Where to stay in Panacea?

Properties are selected based on real traveller reviews and popularity among guests who’ve booked a night in Panacea on Hotels.com. These Panacea hotels consistently deliver on quality, location and traveller experience. Last updated on October 1, 2026.

1. The Panacea Motel

The Panacea Motel
Panacea
P7,456
P8,313 total
includes taxes & fees
Oct 1 - Oct 2
The Panacea Motel

2. Best Western Wakulla Inn & Suites

Best Western Wakulla Inn & Suites
Crawfordville
P7,260
P8,094 total
includes taxes & fees
Oct 14 - Oct 15
Best Western Wakulla Inn & Suites

3. Wildwood Inn

Wildwood Inn
Crawfordville
P7,285
P8,373 total
includes taxes & fees
Oct 22 - Oct 23
Wildwood Inn

4. The Lodge at Wakulla Springs

The Lodge at Wakulla Springs
Crawfordville
P5,585
P6,228 total
includes taxes & fees
Oct 15 - Oct 16
The Lodge at Wakulla Springs

5. St James Bay Golf & Pickleball Resort

St James Bay Golf & Pickleball Resort
Carrabelle
P6,524
P9,503 total
includes taxes & fees
Oct 1 - Oct 2
St James Bay Golf & Pickleball Resort

6. The Moorings Hotel and Marina

The Moorings Hotel and Marina
Carrabelle
P8,637
P9,544 total
includes taxes & fees
Oct 1 - Oct 2
The Moorings Hotel and Marina

7. The Old Carrabelle Hotel

The Old Carrabelle Hotel
Carrabelle
P6,590
P7,282 total
includes taxes & fees
Oct 13 - Oct 14
The Old Carrabelle Hotel

8. Franklin Inn

Franklin Inn
Carrabelle
P5,350
P5,912 total
includes taxes & fees
Oct 1 - Oct 2
Franklin Inn
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Go beyond your typical stay in Panacea

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Pet friendly
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Our prices for hotels in Panacea are cheapest in February

Price trends for hotels in Panacea

Pricing is based on two traveler single night rates
View properties in September

September

High 30°C / low 23°C. Sunny most days.
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11°
17°
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25°
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Monthly weather averages (˚C)

Top landmarks in Panacea

Alligator Point Beach

8.8/10 (10 reviews)
When the beach is calling your name, you might want to head down to Alligator Point Beach, located 4.5 mi (7.2 km) from central Alligator Point. Enjoy the sunset by the shore at Wilson Beach.
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Bald Point State Park

8.6/10 (20 reviews)
Bald Point State Park is 1.7 mi (2.7 km) from central Alligator Point, why not stop by during your stay.
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Mashes Sand Beach

8.8/10 (3 reviews)
If being by the water is a major draw, Mashes Sand Beach is a spot you might want to check out, located 5.1 mi (8.2 km) from central Panacea. If you want to continue walking by the waves, head to Shell Point Beach, Wilson Beach, and Alligator Point Beach.
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beach near Alligator Point Marina

When the beach is calling your name, you might want to head down to beach near Alligator Point Marina, located 3 mi (4.8 km) from central Alligator Point. If you want to continue walking by the waves, head to Alligator Point Beach and Wilson Beach.
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Wilson Beach

Whether you want to collect beach glass or watch the sunset, Wilson Beach is a spot you might want to check out, located 7.4 mi (11.9 km) from central Panacea. Enjoy the sunset by the shore at Alligator Point Beach.
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beach near Alligator Point

When the beach is calling your name, you might want to head down to beach near Alligator Point, located 2.7 mi (4.4 km) from central Alligator Point. If you want to continue walking by the waves, head to Alligator Point Beach and Wilson Beach.
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beach near Summer Camp Beach

Whether you want to collect beach glass or watch the sunset, beach near Summer Camp Beach is a spot you might want to check out, located 10.3 mi (16.6 km) from central Panacea. If you want to continue walking by the waves, head to Alligator Point Beach and Wilson Beach.
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Public Beach Access

Public Beach Access is 2.3 mi (3.7 km) from central Alligator Point, why not stop by during your stay. Want to stretch your legs some more? Head to Alligator Harbor Aquatic Preserve, located nearby.
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Learn more about Panacea

Notable for its natural beauty, Panacea features attractions such as Mashes Sand Beach and Alligator Point Beach. This beachside city has something for everyone including seafood restaurants as well as sights like Bald Point State Park and Wilson Beach. All are within a secluded setting.

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A coastal resort with beachfront villas and a clear blue sky.

Find out more about Panacea

Whispers of the Wild: Discover the Hidden Coastal Gem of Panacea

Discover Panacea, Florida – a charming coastal haven where pristine beaches meet untouched nature. Renowned for its serene shoreline and inviting atmosphere, Panacea offers a perfect retreat for lovers of the outdoors. Explore the natural beauty of the Panacea area, unwind on soft sandy beaches, and savour the tranquillity of this hidden gem. Whether it’s a leisurely stroll along the coast or an adventurous excursion into the surrounding landscapes, Panacea promises a refreshing escape from the everyday bustle. Experience the allure of Florida’s best-kept secret, where every moment is infused with the spirit of coastal bliss.

Discover great hotels near Panacea

In Panacea, Florida, you'll find a mix of accommodation options, from charming motels to budget-friendly hotels, often featuring free cancellation. Room rates vary widely, catering to different budgets, making it easy to find something that suits your needs while enjoying the natural beauty of the area. Here are some of our travelers' favorite hotels near Panacea:

  1. Best Western Wakulla Inn & Suitesopens in new window: This 3-star hotel boasts a guest rating of 8.8 out of 10, offering adventure seekers a dynamic and vibrant setting. Guests can delight in an array of on-site and nearby adventure sports including boat tours, hiking and biking, snorkelling, bicycle rental, and kayaking. The hotel celebrates its welcoming design with an emphasis on express check-in and curated local experiences, making for a smooth and memorable stay. Its contemporary architectural design and high-end facilities cater to leisure travellers who value a distinctive and quality journey.
  2. Wildwood Innopens in new window: This 3.0-star hotel shines with a guest rating of 8.6 out of 10, perfect for leisure travellers looking for an active and energetic retreat. With a focus on adventure, the hotel offers exciting activities including fishing, sailing, kayaking, snorkelling, and mountain biking. The property features a modern aesthetic with highlights such as efficient express check-in and thoughtfully curated experiences that ensure a seamless and engaging stay. Guests appreciate the clean and well-appointed rooms and the inviting ambience created by high-end restaurants and stylish architectural touches.
  3. St James Bay Golf & Pickleball Resortopens in new window: This 3.5-star hotel features a guest rating of 9.0 out of 10, making it an exceptional choice for leisure travellers with a penchant for distinctive experiences. The hotel offers a blend of adventure sports such as windsurfing, hunting, kayaking, surfing and bodyboarding, and fishing, alongside a focus on golf-themed leisure. Its elegant setting is enhanced by curated experiences, express check-in, and a sophisticated design that includes high-end restaurant options. The property exudes a boutique charm, promising a smooth and enriched journey for those seeking an elevated travel experience.

Where to stay in and around Panacea

Alligator Point, Crawfordville, Saint Teresa in Panacea, Florida offer diverse attractions. Alligator Point boasts scenic views and relaxation, while Crawfordville charms with nature, hiking, wildlife, and family-friendly activities. Saint Teresa provides a peaceful retreat. For first-time visitors, Crawfordville is best suited, offering a balanced blend of adventure and tranquillity in the Panacea area.

  1. Alligator Pointopens in new window: Alligator Point is a hidden gem for nature lovers, offering stunning beaches and a peaceful atmosphere. It's a fantastic spot for relaxing by the water or exploring the scenic coastal landscapes. The area is known for its wildlife, making it perfect for birdwatching and enjoying the natural surroundings. With beautiful views and a laid-back vibe, it's an ideal choice for families and those looking to unwind. Accommodations here often feature beach access and are close to outdoor activities like boating and fishing.
  2. Crawfordvilleopens in new window: Crawfordville is a charming destination that combines family-friendly activities with abundant nature. This area is perfect for hiking and exploring local forests, where you can immerse yourself in the rich wildlife. It's also a great base for boating adventures, allowing you to experience the area's waterways. The welcoming community and relaxed atmosphere make it an appealing choice for families and outdoor enthusiasts. You’ll find various comfortable stays that cater to those looking for a serene getaway.
  3. Saint Teresaopens in new window: Saint Teresa offers a tranquil escape with its beautiful beaches and serene environment. This location is particularly attractive for those seeking a quiet retreat away from the hustle and bustle. Enjoy the pristine coastline and the relaxed pace of life, perfect for sunbathing or leisurely walks along the shore. It's an excellent choice for visitors wanting to connect with nature and unwind. Accommodations range from cozy cottages to charming inns, providing a homely feel while being close to the beach.

Things to do in Panacea

Panacea is a delightful retreat boasting pristine beaches and lush forests, perfect for boating, sea diving, and hiking. Enjoy dolphin spotting, fishing trips, and breathtaking sunsets. With comfortable Panacea hotels available, this destination offers a refreshing blend of coastal and natural wonders for travellers.

  • Shell Point Beachopens in new window – Spend a relaxing day soaking up the sun on the sandy shores of Shell Point Beach. This lovely spot invites you to take leisurely strolls along the shoreline, collect unique shells, and enjoy the tranquil views of the Gulf of Mexico.
  • Wakulla Springs State Parkopens in new window – Dive into the natural beauty of Wakulla Springs State Park, where you can explore lush landscapes and spot diverse wildlife. The crystal-clear springs are perfect for a refreshing swim or a peaceful boat tour, offering a glimpse of the area's rich ecosystems.
  • St. Marks National Wildlife Refugeopens in new window – Discover the stunning habitats at St. Marks National Wildlife Refuge. With miles of scenic trails, you can hike or bike while keeping an eye out for birds and other wildlife. The picturesque coastal views provide a perfect backdrop for photography enthusiasts.
  • Ochlockonee River State Parkopens in new window – Navigate the serene waters of the Ochlockonee River State Park, where you can kayak or fish amid beautiful surroundings. The park offers numerous trails for hiking, showcasing the area's rich flora and fauna.
  • Alligator Point Beachopens in new window – Venture to Alligator Point Beach for a quieter beach experience. Here, you can enjoy the gentle waves, perfect for swimming, or simply relax with a good book while listening to the sounds of nature.

4 tips for savvy savings when booking a hotel in Panacea

  1. Book for the cheapest times: The most budget-friendly times to visit Panacea are in January, July, and December, when hotel prices are generally lower. For those looking to immerse themselves in the area's landmarks, history, and culture, a stay of at least 2 to 3 days is recommended. During this time, visitors can enjoy the beautiful beaches, witness dolphins, savour delicious seafood, and relish in the tranquillity of secluded spots. Additionally, opportunities for fishing, nature exploration, wildlife observation, and breathtaking sunsets further enhance the experience, making it a great value for money trip.
  2. Look for last-minute deals on Hotels.com: At Panacea, you may discover hotel deals by exploring the Dealsopens in new window section on Hotels.com. For those seeking last-minute bargains, the Last-Minute Deals area could offer discounted stays near your travel date. By enabling alerts and notifications, you're more likely to see flash sales and special promotions. Additionally, the Smart Shopping feature allows you to compare hotel prices and amenities within the app, ensuring you find the best deal on Panacea hotels.
  3. Be flexible with dates: Prices may fluctuate depending on factors such as the hotel's location, star rating, and the time of year; therefore, being flexible with your travel dates could assist you in finding a more affordable stay at the Panacea hotel. For those seeking a distinctive experience, boutique hotels often provide a more personalised touch and may offer better value. When you make a booking through Hotels.com, we will inform you if the price for your chosen dates is above or below the average. Should the price be on the higher side, we can recommend alternative dates that might help you find a more favourable rate.
  4. Consider your location: Choosing accommodation nearer to key attractions or city centres may provide convenience, but it often comes with a higher price tag. For those seeking more affordable options, consider hotels situated in less central areas or neighbourhoods, allowing you to balance cost with accessibility to the sites you wish to visit. You might also look into independent hotels located a bit further out, which are usually more likely to be affordable and can offer a more authentic experience.

Best time to go to Panacea

Panacea experiences its lowest average temperature in January, at 53.6°F (12.0°C), while July to August are the hottest months, with an average temperature of 81.7°F (27.6°C). August is typically the wettest month. If you’re looking to soak up the lively atmosphere in Panacea, April, June, and July are the peak months to visit, bustling with fellow travelers. During this peak period, the weather is mostly sunny, with light to moderate rainfall. However, if you prefer a more relaxed experience, October to December are perfect for a quieter getaway, marked by light rainfall and mostly sunny conditions.

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