Hotels in Cairo

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Nov 12 - Nov 13
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Nov 13 - Nov 14
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Nov 13 - Nov 15
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Nov 20 - Nov 22

Where to stay in Cairo?

Properties are selected based on real traveller reviews and popularity among guests who’ve booked a night in Cairo on Hotels.com. These Cairo hotels consistently deliver on quality, location and traveller experience. Last updated on November 13, 2026.
A hotel lobby with a reception desk, two armchairs, a coffee table, and large windows with potted plants.

1. Quality Inn Cairo I-57

Quality Inn Cairo I-57
2.5 star property
Cairo
6.4 out of 10, Good, (297 reviews)
Set off I-57 in Cairo, this welcoming hotel provides complimentary full breakfast and self parking. Explore nearby Fort Defiance State Park or take a short drive to Ballard Wildlife Management Area while enjoying free WiFi throughout your stay.
The price is P4,441
P4,928 total
includes taxes & fees
Dec 4 - Dec 5
Quality Inn Cairo I-57
A hotel room with a large bed, two bedside lamps, a framed picture of a bridge, and a wooden nightstand with a phone.

2. Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
2.0 star property
Charleston
6.8 out of 10, Good, (686 reviews)
This Charleston motel offers complimentary WiFi, parking, and on-the-go breakfast daily. Located with convenient interstate access to Cape Girardeau, guests consistently praise the helpful staff. The comfortable accommodations provide a practical base for exploring southeastern Missouri.
The price is P3,710
P4,155 total
includes taxes & fees
Dec 1 - Dec 2
Super 8 by Wyndham Charleston/Sikeston East MO
A hotel room with two beds, a nightstand, a lamp, and a window with curtains.

3. Eagle Inn Charleston

Eagle Inn Charleston
2.0 star property
Charleston
6.6 out of 10, Good, (107 reviews)
Active travelers will appreciate the health club at this comfortable Charleston motel. Free WiFi keeps you connected, while complimentary parking saves you money. Located within driving distance of Cape Girardeau Municipal Airport for easy regional access.
The price is P4,174
P4,674 total
includes taxes & fees
Nov 13 - Nov 14
Eagle Inn Charleston
A reception desk with a computer, a framed picture on the wall, and a vase with flowers.

4. La Center Motel

La Center Motel
2.0 star property
La Center
8.0 out of 10, Very good, (25 reviews)
Escape to this relaxing La Center hotel with complimentary WiFi and parking. Just a 15-minute drive from Ohio River Valley and 16 minutes from Paducah Regional Airport, the convenient location makes exploring the area effortless.
The price is P3,399
P3,976 total
includes taxes & fees
Nov 24 - Nov 25
La Center Motel
A building with a fountain and flower beds in front.

5. The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston
2.5 star property
Charleston
6.8 out of 10, Good, (443 reviews)
The price is P4,206
P4,709 total
includes taxes & fees
Nov 15 - Nov 16
The Riverstone Hotel Charleston-Sikeston
A modern kitchen with white cabinetry, stainless steel appliances, and a window with a view of greenery.

6. Quiet Country Stay: Modern Home Near Paducah

Quiet Country Stay: Modern Home Near Paducah
3.0 star property
Cunningham
The price is P9,425
P18,374 total
includes taxes & fees
Nov 23 - Nov 24
Quiet Country Stay: Modern Home Near Paducah
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Go beyond your typical stay in Cairo

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When is the best time to visit Cairo?

Our prices for hotels in Cairo are cheapest in January

Price trends for hotels in Cairo

Pricing is based on two traveler single night rates
View properties in November
Currently viewing crowd sizes and weather for November.

November

High 14°C / low 5°C. Partly sunny.
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November, no crowd data, average high temperature 14 degrees Celsius, average low temperature 5 degrees Celsius. Partly sunny.
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December, no crowd data, average high temperature 9 degrees Celsius, average low temperature 1 degrees Celsius. Partly sunny.
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January, no crowd data, average high temperature 6 degrees Celsius, average low temperature -2 degrees Celsius. Partly sunny.
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February, no crowd data, average high temperature 8 degrees Celsius, average low temperature -1 degrees Celsius. Partly sunny.
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March, no crowd data, average high temperature 14 degrees Celsius, average low temperature 5 degrees Celsius. Partly sunny.
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April, no crowd data, average high temperature 19 degrees Celsius, average low temperature 9 degrees Celsius. Sunny most days.
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May, no crowd data, average high temperature 25 degrees Celsius, average low temperature 15 degrees Celsius. Sunny most days.
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June, no crowd data, average high temperature 30 degrees Celsius, average low temperature 20 degrees Celsius. Sunny most days.
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July, no crowd data, average high temperature 32 degrees Celsius, average low temperature 21 degrees Celsius. Sunny most days.
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August, no crowd data, average high temperature 31 degrees Celsius, average low temperature 20 degrees Celsius. Sunny most days.
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September, no crowd data, average high temperature 28 degrees Celsius, average low temperature 17 degrees Celsius. Sunny most days.
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October, no crowd data, average high temperature 21 degrees Celsius, average low temperature 11 degrees Celsius. Sunny most days.
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Monthly weather averages (˚C)

Top landmarks in Cairo

Fort Defiance State Park

7.4/10 (15 reviews)
Fort Defiance State Park is 2.3 mi (3.7 km) from central Cairo, why not stop by during your stay.
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Learn more about Cairo

Cairo is well-known for its attractions such as Mississippi River and Ohio River Valley. The city has something for everyone including sights like Fort Defiance State Park within a small-town setting.

See all hotels in Cairo
A steel bridge with a sunset in the background.

Frequently Asked Questions

Can I book refundable accommodations in Cairo?

If you're looking for the flexibility to change your travel plans to Cairo, most hotels offer refundable* bookable rates. You can find these properties by searching our site and using the "fully refundable" filter to narrow the results down.

What will the weather in Cairo be like during my trip?

The warmest months in Cairo are usually July and August with an average temp of 76°F. January and February are the chilliest months when the average temp is 41°F. The rainiest months are April and March.

Why should I book my Cairo accommodation with Hotels.com?

There are plenty of reasons to book your Cairo travel with us: our free cancellations on selected hotels* gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

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