Hotels in Old Appleton

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Top 5 hotels in Old Appleton at a glance

1. The Riverview — 4-star hotel in Cape Girardeau. Guest rating: 9.4/10 — Exceptional.
2. Drury Plaza Hotel Cape Girardeau Conference Center — 3-star hotel in Cape Girardeau. Guest rating: 9.6/10 — Exceptional.
3. Drury Inn & Suites Cape Girardeau — 3-star hotel in Cape Girardeau. Guest rating: 9.4/10 — Exceptional.
4. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau — 3-star hotel in Jackson. Guest rating: 9.0/10 — Wonderful.
5. Pear Tree Inn Cape Girardeau West — 2.5-star hotel in Cape Girardeau. Guest rating: 9.2/10 — Wonderful.

Where to stay in Old Appleton?

Properties are selected based on real traveler reviews and popularity among guests who’ve booked a night in Old Appleton on Hotels.com. These Old Appleton hotels consistently deliver on quality, location and traveler experience. Last updated on October 13, 2026.

A spacious lobby with a curved staircase, large windows, and a seating area with a rug.

A modern living room with a large sectional sofa, a flat-screen TV, and a view of the sea through large windows.

A modern bar area with a herringbone patterned wall, a long counter with bar stools, and a variety of bottles and glasses.

A modern outdoor seating area with a fire feature, a stone wall, and a view of the sunset.

1. The Riverview

Cape Girardeau

$109 nightly

$123 total

Oct 18 - Oct 19

Total with taxes and fees

A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.

An indoor swimming pool with clear blue water, surrounded by beige walls and large windows.

A spacious lobby with a curved seating area, a reception desk, and a large window providing natural light.

A spacious corridor with a high ceiling, recessed lighting, and a series of posters on the walls.

2. Drury Plaza Hotel Cape Girardeau Conference Center

Cape Girardeau

$97 nightly

$109 total

Nov 2 - Nov 3

Total with taxes and fees

A hotel room with a large bed, two bedside lamps, a chair, and a wooden headboard.

A hotel room with a large bed, two bedside tables, a desk with a chair, and two lamps.

A breakfast setting with waffles, scrambled eggs, toast, a glass of orange juice, and a white mug on a table with a green placemat.

A bowl of cereal with raisins and milk, a half orange, and a sandwich on a table with a yellow napkin.

3. Drury Inn & Suites Cape Girardeau

Cape Girardeau

$90 nightly

$102 total

Oct 25 - Oct 26

Total with taxes and fees

A hotel entrance with a large sign reading "LAQUINTA" and a sun graphic.

A hotel room with two beds, a nightstand, a lamp, and a chair.

A reception desk with a large mural of a bridge, wooden reception area, and a potted plant.

An outdoor patio with tables and chairs, a stone wall, and large windows.

4. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Jackson

$80 nightly

$86 total

Nov 1 - Nov 2

Total with taxes and fees

A hotel room with a blue sofa, an orange ottoman, a desk with a lamp, a television, and a window with curtains.

A reception area with a wooden reception desk, two blue armchairs with orange cushions, a patterned side table, and a wall-mounted lamp.

A hotel room with two beds, a window with curtains, an air conditioning unit, and a lamp on a nightstand.

A Dear Tree Inn building with a covered entrance and a clear sky at dusk.

5. Pear Tree Inn Cape Girardeau West

Cape Girardeau

$72 nightly

$81 total

Oct 25 - Oct 26

Total with taxes and fees

A spacious lobby with a large sectional sofa, multiple armchairs, and a coffee table. There is a TV mounted on the wall and a large window providing a view of the outdoors.

A Drury Inn & Suites building with a traditional architectural style, featuring a covered entrance and multiple windows.

A restaurant with a brick wall, a flat-screen TV, and a bar area.

An indoor swimming pool with a wooden ceiling, lounge chairs, and a lifeguard chair.

6. Drury Inn & Suites Jackson MO

Jackson

$80 nightly

$85 total

Oct 18 - Oct 19

Total with taxes and fees

A spacious lobby with a fireplace, comfortable seating, a staircase, and a large chandelier.

An indoor swimming pool with a clear view of the pool area, including the pool's edge, a set of stairs leading into the pool, and a few lounge chairs and tables around the pool.

A spacious hotel lobby with a high ceiling, a central seating area with sofas and chairs, a fireplace, and a television mounted on the wall.

A living room with a stone fireplace, a television mounted above it, and a large sofa with cushions.

7. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Cape Girardeau

$101 nightly

$115 total

Oct 25 - Oct 26

Total with taxes and fees

A hotel room with two beds, a desk, a chair, a TV, and a projector screen.

An indoor swimming pool with four lounge chairs and a metal ladder.

A buffet with various food items, including omelets and other dishes, with clear signage indicating the type of food.

A coffee station with two espresso machines, a coffee press, and various coffee cups and containers.

8. Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

Murphysboro

$108 nightly

$120 total

Nov 1 - Nov 2

Total with taxes and fees

A spacious lobby with marble flooring, elegant seating, and a grand staircase.

A lobby with seating areas, a reception desk, and a bar.

A spacious living room with a sofa set, a coffee table, and a dining area.

A Courtyard by Marriott hotel with a modern brick facade, large windows, and a covered entrance area.

9. Courtyard by Marriott Cape Girardeau Downtown

Cape Girardeau

$125 nightly

$142 total

Oct 25 - Oct 26

Total with taxes and fees

A hotel with a modern design, featuring a prominent sign for Candlewood Suites. There are multiple parking spaces visible in front of the building.

A hotel entrance with a large tree, a well-maintained garden with various plants and flowers, and a parking lot.

An indoor swimming pool with tiled flooring, a seating area with chairs, and a staircase leading to a door.

A hotel patio with a gazebo, outdoor seating, and a view of the road.

10. Candlewood Suites Cape Girardeau by IHG

Cape Girardeau

$82 nightly

$98 total

Oct 25 - Oct 26

Total with taxes and fees

A modern living room with a sofa, armchairs, a coffee table, and a TV mounted on the wall.

An indoor swimming pool with lounge chairs and tables, large windows, and a view of the outside.

A Fairfield by Marriott hotel with a modern design, featuring a stone facade, multiple floors, and a well-lit entrance.

A modern living room with a sofa, a coffee table, and a dining area with chairs and a table.

11. Fairfield Inn & Suites by Marriott Cape Girardeau

Cape Girardeau

$101 nightly

$114 total

Oct 22 - Oct 23

Total with taxes and fees

A modern retail area with a display of local items and snacks.

A modern indoor seating area with blue sofas and tables, a patterned carpet, and large windows offering a view of the outdoors.

A modern lounge area with seating options including sofas, chairs, and a hanging chair, with large windows providing a view of the outdoors.

A hotel room with two beds, a desk, a chair, a TV, and a window with a view.

12. Tru By Hilton Cape Girardeau

Cape Girardeau

$89 nightly

$102 total

Oct 22 - Oct 23

Total with taxes and fees

A hotel room with a large bed, a nightstand, a lamp, a chair, and a mirror.

A gym with treadmills, elliptical machines, and weight equipment.

A Holiday Inn Express & Suites building with a covered entrance and multiple windows.

A kitchen counter with a coffee machine, a kettle, and storage boxes.

13. Holiday Inn Express & Suites Perryville by IHG

Perryville

$101 nightly

$116 total

Nov 1 - Nov 2

Total with taxes and fees

A spacious living area with a high ceiling, a green accent wall, and a wooden balcony railing.

A hotel room with a flat-screen TV, a microwave, a sofa, a lamp, and a window with curtains.

A reception desk with a green wall, a wooden door, and a sign that reads 'QUALITY INN.'

A hotel room with a large bathtub, a bed with a wooden headboard, a nightstand with a lamp, and a painting of a building on the wall.

14. Quality Inn Cape Girardeau North

Cape Girardeau

$59 nightly

$67 total

Nov 1 - Nov 2

Total with taxes and fees

A spacious dining area with high ceilings, large windows, and modern lighting fixtures.

A large indoor swimming pool with clear blue water, surrounded by tiled flooring and blue walls.

A hotel room with a bed, a desk with a television, a chair, a suitcase, and a map on the wall.

An outdoor patio with stone walls, wicker furniture, and large windows.

15. Hampton Inn Cape Girardeau I 55 East

Cape Girardeau

$106 nightly

$119 total

Oct 25 - Oct 26

Total with taxes and fees

A living room with a blue wall, a fireplace, a sofa, and a chair.

A bar area with stools and a counter where a bartender is serving drinks.

A brick building with a sign reading "Mercantile & Hotel".

A hotel room with two beds, a vanity with a mirror, a chair, and a dresser.

16. EC Reed's Mercantile and Hotel

Marble Hill

$117 nightly

$127 total

Oct 15 - Oct 16

Total with taxes and fees

A hotel room with a large bathtub, a sofa, a small table, a TV, and a window with curtains.

A hotel lobby with two sofas, a coffee table, lamps, and a large window with a plant.

A spacious lobby with a checkered floor, two sofas with patterned cushions, a computer desk, and a reception area with a glass door.

A hotel room with a large bed, a desk with a chair, a television, and a small table with a lamp.

17. Super 8 by Wyndham Perryville

Perryville

$68 nightly

$78 total

Nov 8 - Nov 9

Total with taxes and fees

A hotel room with a bed, a desk with a chair, a small table, a sofa, a bathtub, and a window with curtains.

A modern bathroom with a large bathtub, a wooden floor, and a dark wall with a colorful abstract painting.

A room with a fireplace, a mounted deer head, a bookshelf, and two armchairs.

A gym with treadmills, a weight machine, and exercise balls.

18. Baymont by Wyndham Chester IL

Chester

$80 nightly

$89 total

Nov 8 - Nov 9

Total with taxes and fees

A rustic interior with exposed brick walls, wooden railings, and a hanging floral chandelier.

A fireplace with a decorative mantel, a framed sign, and a small table with plants.

A bedroom with a brick wall, a bed with patterned bedding, and a shelf with decorative items.

A building with a dark exterior, a large window, and a sign that reads "The Atrium."

19. The Atrium - A Boutique Hotel

Perryville

$98 nightly

$112 total

Oct 15 - Oct 16

Total with taxes and fees

A modern kitchen with a large island, stainless steel appliances, and exposed brick walls.

A bedroom with a bed, a bench, a ceiling fan, a mirror, and a wooden floor.

A large building with multiple green-roofed structures, surrounded by well-maintained lawns and a parking area.

A hallway with exposed brick walls, wooden flooring, and a white door.

20. Urban Lofts

Perryville

$295 nightly

$338 total

Oct 15 - Oct 16

Total with taxes and fees

View all properties

Go beyond your typical stay in Old Appleton

Pet friendly

Pool

Family friendly

Check out reviews of Old Appleton hotels guests love

Drury Inn & Suites Jackson MO

8/10 Good

"My room was spacious. The staff was amazing. Everything was well kept and maintained. I didn't like that the toilet in my king deluxe room was very short (low). I'm 5' 4" and husband is 6'. I struggled getting up. I'm sure my husband was very uncomfortable as well! Also, the placement of the luggage carts just beyond the entry doors and registration placed immediately left of same doors with a line of standing people seems like a fire hazard and very inconvenient. I struggled to get pass the area with my loaded luggage cart while avoiding empty luggage carts and nearly colliding with an older gentleman."

Quality Inn Perryville I-55

8/10 Good

"Utilitarian hotel room. Clean, neat, well maintained. Refrigerators have freezer compartments. Outlets on lamp bases but no USB charging ports."

Days Inn by Wyndham Perryville

8/10 Good

"."

Super 8 by Wyndham Perryville

10/10 Excellent

"Quick and easy check in. Friendly staff."

Quality Inn Cape Girardeau North

10/10 Excellent

"All in all, wasn't too bad. Is time for some renovation."

Urban Lofts

10/10 Excellent

"Beautiful, clean property in the heart of city center. Many options for food and shopping within short walking distance."

Frequently asked questions

How much does a hotel room cost in Old Appleton?

You can find top hotels in Old Appleton from $67 with options to suit your budget and needs. If you're after an affordable hotel in Old Appleton that meets all of your requirements, set your filters and then sort the results by "Price: low to high".

How can I find deals and earn rewards at Old Appleton hotels?

Discover great deals on Old Appleton hotel stays with Hotels.com. You can also look at hotel prices mid-week or during the low season to find off-peak deals. If it's a spontaneous trip, check out our last-minute deals on Old Appleton hotels.

Can I book Old Appleton hotels with free cancellation?

To book a refundable Old Appleton hotel on Hotels.com, just filter hotels by "Property cancellation options" and select "Fully refundable property". Most hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.

Can I book a refundable hotel in Old Appleton?

If you're looking for the flexibility to change your travel plans to Old Appleton, most hotels offer refundable* bookable rates. You can see these accommodations by searching our site and using the "fully refundable" filter to narrow the results down.

What will the weather in Old Appleton be like during my visit?

The warmest months in Old Appleton are usually July and August with an average temp of 76°F. January and February are the chilliest months when the average temp is 40°F. The rainiest months are April and March.

Why should I book my Old Appleton hotel through Hotels.com?

There are plenty of reasons to book your Old Appleton travel with us: our free cancellations on selected hotels gives you the flexibility you're looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

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