Hotels in Cayo Santa Maria

Photo by Mahfoud Al-Shikh

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Free cancellation

Flexible bookings on most hotels*

Where to stay in Cayo Santa Maria?

Find out more about Cayo Santa Maria

If you're looking to discover somewhere new, look no further than Cayo Santa Maria. Whether you're planning to stay for a night or for the week, the area around Cayo Santa Maria has accommodations to fit every need. Search for hotels in Cayo Santa Maria with Hotels.com by checking our online map. Our map displays the areas and neighborhoods around all Cayo Santa Maria hotels so you can see how close you are from landmarks and attractions, and then refine your search within the larger area. The best Cayo Santa Maria hotel deals are here with our lowest price guarantee.

Frequently asked questions

What accommodations do travelers like in Cayo Santa Maria?
Guests like Grand Memories Santa Maria - All Inclusive, Villa Gaviota Cayo Coco and Sanctuary at Grand Memories Santa Maria - Adults Only - All Inclusive.
Where can I find free parking with my stay in Cayo Santa Maria?
Park your car for free at these properties: Sanctuary at Grand Memories Santa Maria - Adults Only - All Inclusive and Grand Memories Santa Maria - All Inclusive.
Can I book a refundable hotel in Cayo Santa Maria?
If you want the flexibility to change your plans to Cayo Santa Maria, most hotels offer refundable* rates you can book. You can see these accommodations by searching our site and using the “fully refundable” filter to narrow down the results.
Where should I stay in Cayo Santa Maria if I'm looking for an affordable accommodation?
Villa Gaviota Cayo Coco is an accommodation you might want to consider that’ll save you money.
Where can I stay if I'm visiting Cayo Santa Maria for a family-friendly trip?
Parents traveling with children may want to consider Golden Tulip Aguas Claras Resort.
What will the weather in Cayo Santa Maria be like during my vacation?
Cayo Santa Maria is a great place to visit to enjoy the sunshine any time of year with an average temp of 70°F.
Why should I book my Cayo Santa Maria hotel through Hotels.com?
There are lots of reasons to book your Cayo Santa Maria trip with us: our free cancellations on selected hotels* gives you flexibility, our Price Guarantee ensures you always get the lowest price, and you can earn reward nights with our Rewards Program saving your money.