Santa Cruz Luxury Hotels

Photo by Jesus Serra-perez

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Free cancellation

Flexible bookings on most hotels*

Find out more about Santa Cruz

What Is Santa Cruz Like for Luxury Vacations?

From great amenities to excellent service, luxury Santa Cruz hotels are more than just a place to rest your head. You can expect modern conveniences combined with comfortable guestrooms when booking one of our hotels in Santa Cruz. You could even book a hotel room close to sights like Plaza 24 de Septiembre and Santa Cruz Zoo, or find yourself a luxury suite in a quieter area for some rest and relaxation. Whether you're searching for a luxurious hotel in the center of Santa Cruz or something just outside, Hotels.com has an ample choice vacation options that won't disappoint.

What Are Some of the Best Hotels in Santa Cruz?

Top hotel picks in and around Santa Cruz:

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

3.5-star hotel with spa, outdoor pool
  • Free parking • Free WiFi • 3 restaurants • 2 bars • Central location

Sun Hotel

3.5-star hotel with outdoor pool, bar
  • Free parking • Free WiFi • Free airport shuttle • Restaurant • Spacious rooms

Hotel Cortez

3.5-star hotel with outdoor pool, bar
  • Free parking • Free WiFi • 2 restaurants • Spa • Attentive staff

Marriott Santa Cruz de la Sierra Hotel

Luxury hotel with outdoor pool, bar
  • Free parking • Free WiFi • Restaurant • Spa • Attentive staff

Radisson Hotel Santa Cruz

Luxury hotel with golf course, near Ventura Mall
  • Free valet parking • Free WiFi • Free kid's activities • Restaurant • Central location

What Are the Best Things to See and Do in Santa Cruz?

    Shopping
  • Ventura Mall
  • Las Brisas Shopping Center
  • La Recova Artisan Walk

  • Sights & Landmarks
  • Plaza 24 de Septiembre
  • Santa Cruz Zoo
  • Guembe Biocenter

Keep exploring